首页工具

登录

搜索结果

Search Results for " nk inhibitory receptor "

2

抑制剂 & 化合物

11

重组蛋白

如果没找到您满意的产品或者您对产品有其他要求，可以联系我们专业顾问为您提供针对性的合理建议。 QQ咨询网站留言咨询

Cat. No.	Product Name	Target	Signaling Pathways
T76405	[D-Trp2,7,9] Substance P
	[D-Trp2,7,9] Substance P 是一种速激肽 (Neurokinin Receptor) 拮抗剂，对 NK-1、NK-2和 NK-3受体的 Ki 值分别为 1 μM、1.3 μM 和 ~9 μM。
T82609	Dargistotug M-6223
	Dargistotug (M-6223) 是一种靶向 TIGIT 的全人 IgG1 类型单克隆抗体。TIGIT 是一种带有 Ig 结构域和 ITIM 的 T 细胞免疫受体，充当抑制性免疫检查点。Dargistotug 通过与 CD155 等分子结合抑制 NK 细胞活性，减少细胞因子分泌，并能直接或间接地抑制效应 T 细胞活性和上调 Tregs，从而发挥免疫抑制作用。

化合物

[D-Trp2,7,9] Substance P

Cat.No: T76405

Cat.No: T82609

Synonym: M-6223

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPJ-00187	CD300A Protein, Human, Recombinant (hFc & His) CMRF35-like molecule 8,NK inhibitory r...	Human	HEK293 Cells
	CD300A is a single-pass type I membrane protein which belongs to the CD300 family. It contains 1 Ig-like V-type (immunoglobulin-like) domain. The CD300 family of myeloid immunoglobulin receptors includes activating (CD300b, CD300e) and inhibitory members (CD300a, CD300f), as well as molecules presenting a negative charge within their transmembrane domain (CD300c, CD300d). It is expressed not only by natural killer (NK) cells but also by T-cell subsets, B-cells, dendritic cells, mast cells, granu...
TMPJ-00604	KIR2DL4 Protein, Human, Recombinant (His) CD158 Antigen-Like Family Member D,KIR2DL4,MHC Class I N...	Human	HEK293 Cells
	Killer cell immunoglobulin-like receptor 2DL4(KIR2DL4) is a Single-pass type I membrane protein and contains 2 Ig-like C2-type (immunoglobulin-like) domains.It belongs to the immunoglobulin superfamily. KIR2DL4 is expressed in all NK cells and some T cells. KIR2DL4 activates the cytotoxicity of NK cells, despite the presence of an immunoreceptor tyrosine-based inhibition motif (ITIM) in its cytoplasmic tail. The ITIM was not necessary for activation of lysis by KIR2DL4. The activation signal of ...
TMPY-04040	CLEC2D Protein, Rat, Recombinant (hFc) C-type lectin domain family 2, member D	Rat	HEK293 Cells
	Lectin-like transcript 1 (LLT1) encoded by CLEC2D gene is a C-type lectin-like molecule interacting with human CD161 (NKR-P1A) receptor expressed by natural killer cells and subsets of T cells. CLEC2D transcripts were detected primarily in hematopoietic cell lines and were found to be co-induced by the same activation signals. Although very low amounts of putative soluble CLEC2D protein isoforms could be produced by transfectants, CLEC2D isoforms 2 and 4 were efficiently expressed. CLEC2D uses g...
TMPK-00875	CD96 Protein, Human, Recombinant (His & Avi), Biotinylated TACTILE,CD96,DKFZp667E2122,CD96 molecule	Human	HEK293 Cells
	The receptors CD96 and TIGIT are expressed on the surface of T and natural killer (NK) cells, and recent studies suggest both play important inhibitory roles in immune function. CD96 has been shown to modulate immune cell activity in mice, with Cd96-/- mice displaying hypersensitive NK-cell responses to immune challenge and significant tumor resistance. The counterbalance between the putative inhibitory CD96 and TIGIT receptors and the activating receptor, CD226, offers unique strategies for imm...
TMPJ-01086	CD244 Protein, Mouse, Recombinant (His) NK cell type I receptor protein 2B4,Natura...	Mouse	HEK293 Cells
	Natural killer cell receptor 2B4 (2B4/CD244)is a 66 kDa type I transmembrane glycoprotein in the SLAM subgroup of the CD2 protein family. SLAM family proteins have an extracellular domain (ECD) with two or four Ig-like domains and at least two cytoplasmic immunoreceptor tyrosine-based switch motifs (ITSMs). 2B4 interacts with CD48, while other SLAM family proteins interact in a homophilic manner. The mouse 2B4 cDNA encodes a 397 amino acid (aa) precursor that includes a 19 aa signal sequence, a ...
TMPK-00177	LAIR1 Protein, Human, Recombinant (His & Avi) CD305,LAIR1,LAIR-1,HLAIR1	Human	HEK293 Cells
	LAIR1 (leukocyte-associated Ig-like receptor-1, designated CD305) is an approximately 40 kDa type I transmembrane inhibitory glycoprotein belonging to the Ig superfamily.LAIR1 functions as an inhibitory receptor that plays a constitutive negative regulatory role on cytolytic function of natural killer (NK) cells, B-cells and T-cells. Activation by Tyr phosphorylation results in recruitment and activation of the phosphatases PTPN6 and PTPN11. It also reduces the increase of intracellular calcium ...
TMPJ-00538	LILRA3/CD85e Protein, Human, Recombinant (His & Avi), Biotinylated Leukocyte immunoglobulin-like receptor subfamily A ...	Human	HEK293 Cells
	Leukocyte immunoglobulin-like receptor subfamily A member 3 is also known as CD85 antigen-like family member E, Immunoglobulin-like transcript 6, ILT-6, Leukocyte immunoglobulin-like receptor 4, LIR-4 and Monocyte inhibitory receptor HM43/HM31. In humans, it is encoded by the LILRA3 gene. It acts as soluble receptor for class I MHC antigens. Binds both classical and non-classical HLA class I molecules but with reduced affinities compared to LILRB1 or LILRB2.It is detected in B-cells, natural kil...
TMPK-00647	KIR3DL2 Protein, Rhesus macaque, Recombinant (His) KIR3DL2,NKAT-4,NKAT4,p140,CL-5,NK...	Rhesus	HEK293 Cells
	KIR3DL2 is a member of the killer cell immunoglobulin-like receptor (KIR) family that was initially identified at the surface of natural killer (NK) cells. KIR3DL2, also known as CD158k, is expressed as a disulfide-linked homodimer. Each chain is composed of three immunoglobulin-like domains and a long cytoplasmic tail containing two immunoreceptor tyrosine-based inhibitory motifs. KIR3DL2 Protein, Rhesus macaque, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predi...
TMPK-00062	CD160 Protein, Human, Recombinant (His & Avi) BY55FLJ46513,NK28,NK1, BY55,CD160	Human	HEK293 Cells
	CD160 (also Natural killer cell receptor BY55) is a 27 ‑ 30 kDa member of the Ig superfamily. In human, it is expressed principally on nonmyeloid hematopoietic cells. CD160 antigenis a receptor on immune cells capable to deliver stimulatory or inhibitory signals that regulate cell activation and differentiation. Exists as a GPI-anchored and as a transmembrane form, each likely initiating distinct signaling pathways via phosphoinositol 3-kinase in activated NK cells and via LCK and CD247/CD3 zeta...
TMPK-00887	KIR3DL2 Protein, Human, Recombinant (His & Avi) KIR3DL2,p140,NKAT4,NKAT4A,NKAT4B,...	Human	HEK293 Cells
	KIR3DL2 is a member of the killer cell immunoglobulin-like receptor (KIR) family that was initially identified at the surface of natural killer (NK) cells. KIR3DL2, also known as CD158k, is expressed as a disulfide-linked homodimer. Each chain is composed of three immunoglobulin-like domains and a long cytoplasmic tail containing two immunoreceptor tyrosine-based inhibitory motifs. KIR3DL2 Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The pred...
TMPY-05086	KIR2DL5 Protein, Human, Recombinant (hFc) KIR2DL5.1,CD158F,KIR2DL5.3,killer cell immunoglobulin like <...	Human	HEK293 Cells
	KIR2DL5A (Killer Cell Immunoglobulin Like Receptor, Two Ig Domains And Long Cytoplasmic Tail 5A) is a Protein Coding gene. The encoded protein belongs to the immunoglobulin superfamily. The most recently described member of the KIR family, KIR2DL5, is represented in human populations by at least four gene variants, whose exons differ by two to eight nucleotides. KIR2DL5 (CD158f) is the most recently identified inhibitory member of human killer-cell Ig-like receptors (KIRs), which enable NK cells...

重组蛋白

CD300A Protein, Human, Recombinant (hFc & His)

Cat.No: TMPJ-00187

Species: Human

Expression System: HEK293 Cells

KIR2DL4 Protein, Human, Recombinant (His)

Cat.No: TMPJ-00604

Species: Human

Expression System: HEK293 Cells

CLEC2D Protein, Rat, Recombinant (hFc)

Cat.No: TMPY-04040

Species: Rat

Expression System: HEK293 Cells

CD96 Protein, Human, Recombinant (His & Avi), Biotinylated

Cat.No: TMPK-00875

Species: Human

Expression System: HEK293 Cells

CD244 Protein, Mouse, Recombinant (His)

Cat.No: TMPJ-01086

Species: Mouse

Expression System: HEK293 Cells

LAIR1 Protein, Human, Recombinant (His & Avi)

Cat.No: TMPK-00177

Species: Human

Expression System: HEK293 Cells

LILRA3/CD85e Protein, Human, Recombinant (His & Avi), Biotinylated

Cat.No: TMPJ-00538

Species: Human

Expression System: HEK293 Cells

KIR3DL2 Protein, Rhesus macaque, Recombinant (His)

Cat.No: TMPK-00647

Species: Rhesus

Expression System: HEK293 Cells

CD160 Protein, Human, Recombinant (His & Avi)

Cat.No: TMPK-00062

Species: Human

Expression System: HEK293 Cells

KIR3DL2 Protein, Human, Recombinant (His & Avi)

Cat.No: TMPK-00887

Species: Human

Expression System: HEK293 Cells

KIR2DL5 Protein, Human, Recombinant (hFc)

Cat.No: TMPY-05086

Species: Human

Expression System: HEK293 Cells

我们的所有产品和服务仅用于科学研究，不能被用于人体，我们也不向个人提供产品和服务。

Copyright © 2015-2024 TargetMol Chemicals Inc. All rights reserved. 沪ICP备20019793号-4

沪公网安备 31010602006700号

沪公网安备 31010602006700号

TargetMol Loading

联系我们

电话：

400-820-0310

邮箱：

service@tsbiochem.com

QQ：

2881945090（终端用户）

2885109491（经销商）

经销：

终端：

地址：

上海市静安区江场三路238号8楼